The selected publications listed below will provide an insight into our research
Ng Y-K, Grasso M, Wright V, Garcia V, Williams P, Atkinson S. (2018). The Quorum Sensing System of Yersinia enterocolitica 8081 Regulates Swimming Motility, Host Cell Attachment, and Virulence Plasmid Maintenance. Genes. 9: 307-321. (doi.org/10.3390/genes9060307)
Atkinson, S. and Williams P. Yersinia virulence factors - a sophisticated arsenal for combating host defences. F1000Research (2016), 5(F1000 Faculty Rev):1370 (doi: 10.12688/f1000research.8466.1)
Condori, S., Atkinson, S., Leys, N., Wattiez, R. and Mastroleo, F. (2016). Construction and phenotypic characterization of M68, an RruI quorum sensing knockout mutant of the photosynthetic alphaproteobacterium Rhodospirillum rubrum. Res.Microbiol. 67: 380-392. (doi:10.1016/j.resmic.2016.02.006).
Joshua, G.W.P., Atkinson, S., Goldstone, R.J., Patrick, H.L., Stabler, R., Purves, J., Cámara, M., Williams, P. and Wren, B.W. (2015). Genome-wide evaluation of the interplay between Caenorhabditis elegans and Yersinia pseudotuberculosis during in vivo biofilm formation. Inf Imm. 83: 17-27. doi: 10.1128/IAI.00110-14.
Twigg, M.S., Tait, K., Williams, P., Atkinson, S. and Cámara, M. (2014). Interference with the germination and growth of Ulva zoospores by quorum sensing molecules produced by Ulva-associated epiphytic bacteria. Env. Micro. 16(2) 445–453. (doi: 10.1111/1462-2920.12203).
Mastroleo, F., Van Houdt, R., Atkinson, S., Mergeay, M., Hendrickx, L., Wattiez, R. and Leys, N. (2013). Modelled microgravity cultivation modulates N-acylhomoserine lactone production in Rhodospirillum rubrum S1H independently of cell density. Microbiology. 159: 2456–2466. (doi:10.1099/mic.0.066415-0).
Hook, A.L., Chang, C., Yang, J., Atkinson, S., Langer, R., Anderson, D.G., Davies, M.C., Williams, P. and Alexander, M.R. (2013). Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays. Adv. Mater. 25: 2542–2547. (doi: 10.1002/adma.201204936).
Hargreaves, C.E., Grasso, M., Hampe, C., Stenkova, A., Atkinson, S., Joshua, G.W.P., W Wren, B., Buckle, A.M., Dunn-Walters, D.K. and Banga, J.S. (2013). Yersinia enterocolitica provides the link between thyroid stimulating antibodies and their germline counterparts in Graves disease. J. Immunol. 190: 5373-5381. (doi: 10.4049/jimmunol.1203412).
Hook, A.L., Chang, C., Yang, J., Luckett, J., Cockayne, A., Atkinson, S., Mei, Y., Bayston, R., Irvine, D.J., Langer, R., Anderson, D.G., Williams, P., Davies, M.C. and Alexander, M.R. (2012) Combinatorial discovery of polymers resistant to bacterial attachment. Nat. Biotech. 30: 868-875. (doi: 10.1038/nbt.2316).
Hothersall, J., Iqbal, Z., Campbell, G., Stephens, E.R., Wu, J., Cooper, H., Atkinson, S., Williams, P., Crosby, J., Willis, C.L., Cox, R.J., Simpson, T.J., and Thomas, C.M. (2011). Manipulation of quorum sensing regulation in Pseudomonas fluorescens NCIMB 10586 to increase mupirocin production. Appl. Microbiol. Biot. 90: 1017-1026. (doi: 10.1007/s00253-011-3145-2).
Strong, P.C.R., Hinchliffe, S.J., Patrick, H., Atkinson S., Champion, O.L. and Wren, B.W. (2011). Identification and characterisation of a novel adhesin Ifp in Yersinia pseudotuberculosis. BMC Microbiol. 11:85. 1-16. (doi: 10.1186/1471-2180-11-85).
Chan K.G., Atkinson S., Mathee K., Sam C.K., Chhabra S.R., Cámara M., Koh C.L. and Williams P. (2011). Characterization of N-acylhomoserine lactone-degrading bacteria associated with the Zingiber officinale (ginger) rhizosphere: co-existence of quorum quenching and quorum sensing in Acinetobacter and Burkholderia. BMC Microbiol. 11:51. 1-13. (doi:10.1186/1471-2180-11-51).
Atkinson, S., Goldstone, R.J., Joshua, G.W.P., Chang, C., Patrick, H.L., Cámara, M., Wren, B.W. amd Williams, P. (2011) Biofilm development on Caenorhabditis elegans by Yersinia is facilitated by quorum sensing-dependent repression of type III secretion. PLOS Pathog. 7(1): e1001250. (doi:10.1371/journal.ppat.1001250).
Czajkowski, R., Krzyżanowska, D., Karczewska, J., Atkinson, S., Przysowa, J., Lojkowska, E., Williams, P. and Jafra, S. (2010) Inactivation of AHLs by Ochrobactrum sp. A44 depends on the activity of a novel class of AHL acylase. Env. Micro Rep. 3. 59-68. (doi: 10.1111/j.1758-2229.2010.00188.x). (doi: 10.1007/s11274-010-0321-y).
Atkinson, S. and Williams, P. (2009) Quorum sensing and social networking in the bacterial world. Interface. 6: 959-978. (doi: 10.1098/rsif.2009.0203).
Hu, Y., Wang, Y., Ding, L., Lu, P., Atkinson, S. and Chen, S. (2009) Positive regulation of flhDC expression by OmpR in Yersinia pseudotuberculosis. Microbiology. 155: 3622 - 3631. (doi: 10.1099/mic.0.030908-0).
Hu, Y., Lu, P., Wang, Y., Ding, L., Atkinson, S. and Chen, S. (2009) OmpR positively regulates urease expression to enhance acid survival of Yersinia pseudotuberculosis. Microbiology. 155: 2522-2531. (doi: 10.1099/mic.0.028381-0.).
Ding, L., Wang, Y., Hu, Y., Atkinson, S., Williams, P. and Chen, S. (2009) Functional characterization of FlgM in the regulation of flagellar synthesis and motility in Yersinia pseudotuberculosis. Microbiology. 155: 1890 – 1900. (doi: 10.1099/mic.0.026294-0).
Tate, K., Williamson, H., Atkinson, S., Williams, P., Cámara, M. and Joint, I. (2009) Turnover of Quorum-Sensing Signal Molecules Modulates Cross-Kingdom Signalling. Env. Microbiol. 11: 1792-1802. (doi: 10.1111/j.1462-2920.2009.01904.x).
Atkinson, S., Chang, C., Patrick, H.L., Buckley, C.M.F., Wang, Y., Sockett, R.E., Cámara, M. and Williams, P. (2008) Functional Interplay Between the Yersinia pseudotuberculosis YpsRI and YtbRI Quorum Sensing Systems Modulates Swimming Motility by Controlling Expression of flhDC and fliA. Mol. Microbiol. 69: 137-151. (doi: 10.1111/j.1365-2958.2008.06268.x).
Atkinson, S., Ortori, C. A., Chhabra, S.R., Cámara, C., Barrett, D.A. and Williams, P. (2007) Comprehensive Profiling of N-acylhomoserine Lactones Produced by Yersinia pseudotuberculosis using Liquid Chromatography Coupled to Hybrid Quadrupole-Linear Ion Trap Mass Spectrometry. Anal. Bioanal. Chem. 387: 497-511. (doi: 10.1007/s00216-006-0710-0).
Atkinson, S., Chang, C., Sockett, R.E., Camara, M. and Williams, P. (2006) Quorum Sensing in Yersinia enterocolitica Controls Swimming and Swarming Motility. J. Bacteriol. 181: 2823-2833. (doi: 10.1128/JB.188.4.1451-1461.2006).
Atkinson, S., Sockett, R.E., Camara, M. and Williams, P. (2006) Quorum Sensing and the Lifestyle of Yersinia. Curr. Issues Mol. Biol. 8: 1-10.
Yates, E.A., Philipp, B., Buckley, C.M.F., Atkinson, S., Chhabra, S.R., Sockett, R.E., Camara, M., Goldner, M., Smith, H. and Williams, P. (2002) N-Acylhomoserine Lactones Undergo Lactonolysis in a pH, Temperature and Acyl Chain Length Dependent Manner During Growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa. Infect. Immun. 70: 5635-5646. (doi: 10.1128/IAI.70.10.5635-5646.2002).
Atkinson, S., Throup, J.P., Williams, P. and Stewart, G.S.A.B. (1999) A Hierarchical Quorum Sensing System in Yersinia pseudotuberculosis is Involved in the Regulation of Motility and Clumping. Mol. Microbiol. 38: 1267-1277. (doi: 10.1046/j.1365-2958.1999.01578.x)
Atkinson, S. and Williams P. Yersinia virulence factors - a sophisticated arsenal for combating host defences. F1000Research (2016), 5(F1000 Faculty Rev):1370 (doi: 10.12688/f1000research.8466.1)
Condori, S., Atkinson, S., Leys, N., Wattiez, R. and Mastroleo, F. (2016). Construction and phenotypic characterization of M68, an RruI quorum sensing knockout mutant of the photosynthetic alphaproteobacterium Rhodospirillum rubrum. Res.Microbiol. 67: 380-392. (doi:10.1016/j.resmic.2016.02.006).
Joshua, G.W.P., Atkinson, S., Goldstone, R.J., Patrick, H.L., Stabler, R., Purves, J., Cámara, M., Williams, P. and Wren, B.W. (2015). Genome-wide evaluation of the interplay between Caenorhabditis elegans and Yersinia pseudotuberculosis during in vivo biofilm formation. Inf Imm. 83: 17-27. doi: 10.1128/IAI.00110-14.
Twigg, M.S., Tait, K., Williams, P., Atkinson, S. and Cámara, M. (2014). Interference with the germination and growth of Ulva zoospores by quorum sensing molecules produced by Ulva-associated epiphytic bacteria. Env. Micro. 16(2) 445–453. (doi: 10.1111/1462-2920.12203).
Mastroleo, F., Van Houdt, R., Atkinson, S., Mergeay, M., Hendrickx, L., Wattiez, R. and Leys, N. (2013). Modelled microgravity cultivation modulates N-acylhomoserine lactone production in Rhodospirillum rubrum S1H independently of cell density. Microbiology. 159: 2456–2466. (doi:10.1099/mic.0.066415-0).
Hook, A.L., Chang, C., Yang, J., Atkinson, S., Langer, R., Anderson, D.G., Davies, M.C., Williams, P. and Alexander, M.R. (2013). Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays. Adv. Mater. 25: 2542–2547. (doi: 10.1002/adma.201204936).
Hargreaves, C.E., Grasso, M., Hampe, C., Stenkova, A., Atkinson, S., Joshua, G.W.P., W Wren, B., Buckle, A.M., Dunn-Walters, D.K. and Banga, J.S. (2013). Yersinia enterocolitica provides the link between thyroid stimulating antibodies and their germline counterparts in Graves disease. J. Immunol. 190: 5373-5381. (doi: 10.4049/jimmunol.1203412).
Hook, A.L., Chang, C., Yang, J., Luckett, J., Cockayne, A., Atkinson, S., Mei, Y., Bayston, R., Irvine, D.J., Langer, R., Anderson, D.G., Williams, P., Davies, M.C. and Alexander, M.R. (2012) Combinatorial discovery of polymers resistant to bacterial attachment. Nat. Biotech. 30: 868-875. (doi: 10.1038/nbt.2316).
Hothersall, J., Iqbal, Z., Campbell, G., Stephens, E.R., Wu, J., Cooper, H., Atkinson, S., Williams, P., Crosby, J., Willis, C.L., Cox, R.J., Simpson, T.J., and Thomas, C.M. (2011). Manipulation of quorum sensing regulation in Pseudomonas fluorescens NCIMB 10586 to increase mupirocin production. Appl. Microbiol. Biot. 90: 1017-1026. (doi: 10.1007/s00253-011-3145-2).
Strong, P.C.R., Hinchliffe, S.J., Patrick, H., Atkinson S., Champion, O.L. and Wren, B.W. (2011). Identification and characterisation of a novel adhesin Ifp in Yersinia pseudotuberculosis. BMC Microbiol. 11:85. 1-16. (doi: 10.1186/1471-2180-11-85).
Chan K.G., Atkinson S., Mathee K., Sam C.K., Chhabra S.R., Cámara M., Koh C.L. and Williams P. (2011). Characterization of N-acylhomoserine lactone-degrading bacteria associated with the Zingiber officinale (ginger) rhizosphere: co-existence of quorum quenching and quorum sensing in Acinetobacter and Burkholderia. BMC Microbiol. 11:51. 1-13. (doi:10.1186/1471-2180-11-51).
Atkinson, S., Goldstone, R.J., Joshua, G.W.P., Chang, C., Patrick, H.L., Cámara, M., Wren, B.W. amd Williams, P. (2011) Biofilm development on Caenorhabditis elegans by Yersinia is facilitated by quorum sensing-dependent repression of type III secretion. PLOS Pathog. 7(1): e1001250. (doi:10.1371/journal.ppat.1001250).
Czajkowski, R., Krzyżanowska, D., Karczewska, J., Atkinson, S., Przysowa, J., Lojkowska, E., Williams, P. and Jafra, S. (2010) Inactivation of AHLs by Ochrobactrum sp. A44 depends on the activity of a novel class of AHL acylase. Env. Micro Rep. 3. 59-68. (doi: 10.1111/j.1758-2229.2010.00188.x). (doi: 10.1007/s11274-010-0321-y).
Atkinson, S. and Williams, P. (2009) Quorum sensing and social networking in the bacterial world. Interface. 6: 959-978. (doi: 10.1098/rsif.2009.0203).
Hu, Y., Wang, Y., Ding, L., Lu, P., Atkinson, S. and Chen, S. (2009) Positive regulation of flhDC expression by OmpR in Yersinia pseudotuberculosis. Microbiology. 155: 3622 - 3631. (doi: 10.1099/mic.0.030908-0).
Hu, Y., Lu, P., Wang, Y., Ding, L., Atkinson, S. and Chen, S. (2009) OmpR positively regulates urease expression to enhance acid survival of Yersinia pseudotuberculosis. Microbiology. 155: 2522-2531. (doi: 10.1099/mic.0.028381-0.).
Ding, L., Wang, Y., Hu, Y., Atkinson, S., Williams, P. and Chen, S. (2009) Functional characterization of FlgM in the regulation of flagellar synthesis and motility in Yersinia pseudotuberculosis. Microbiology. 155: 1890 – 1900. (doi: 10.1099/mic.0.026294-0).
Tate, K., Williamson, H., Atkinson, S., Williams, P., Cámara, M. and Joint, I. (2009) Turnover of Quorum-Sensing Signal Molecules Modulates Cross-Kingdom Signalling. Env. Microbiol. 11: 1792-1802. (doi: 10.1111/j.1462-2920.2009.01904.x).
Atkinson, S., Chang, C., Patrick, H.L., Buckley, C.M.F., Wang, Y., Sockett, R.E., Cámara, M. and Williams, P. (2008) Functional Interplay Between the Yersinia pseudotuberculosis YpsRI and YtbRI Quorum Sensing Systems Modulates Swimming Motility by Controlling Expression of flhDC and fliA. Mol. Microbiol. 69: 137-151. (doi: 10.1111/j.1365-2958.2008.06268.x).
Atkinson, S., Ortori, C. A., Chhabra, S.R., Cámara, C., Barrett, D.A. and Williams, P. (2007) Comprehensive Profiling of N-acylhomoserine Lactones Produced by Yersinia pseudotuberculosis using Liquid Chromatography Coupled to Hybrid Quadrupole-Linear Ion Trap Mass Spectrometry. Anal. Bioanal. Chem. 387: 497-511. (doi: 10.1007/s00216-006-0710-0).
Atkinson, S., Chang, C., Sockett, R.E., Camara, M. and Williams, P. (2006) Quorum Sensing in Yersinia enterocolitica Controls Swimming and Swarming Motility. J. Bacteriol. 181: 2823-2833. (doi: 10.1128/JB.188.4.1451-1461.2006).
Atkinson, S., Sockett, R.E., Camara, M. and Williams, P. (2006) Quorum Sensing and the Lifestyle of Yersinia. Curr. Issues Mol. Biol. 8: 1-10.
Yates, E.A., Philipp, B., Buckley, C.M.F., Atkinson, S., Chhabra, S.R., Sockett, R.E., Camara, M., Goldner, M., Smith, H. and Williams, P. (2002) N-Acylhomoserine Lactones Undergo Lactonolysis in a pH, Temperature and Acyl Chain Length Dependent Manner During Growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa. Infect. Immun. 70: 5635-5646. (doi: 10.1128/IAI.70.10.5635-5646.2002).
Atkinson, S., Throup, J.P., Williams, P. and Stewart, G.S.A.B. (1999) A Hierarchical Quorum Sensing System in Yersinia pseudotuberculosis is Involved in the Regulation of Motility and Clumping. Mol. Microbiol. 38: 1267-1277. (doi: 10.1046/j.1365-2958.1999.01578.x)