Our Yersinia enterocolitica research
Introduction
Y. enterocolitica is a mammalian enteropathogen which can present in humans as enteritis, enterocolitis, mesenteric lymphadenitis or terminal ileitis normally after the consumption of contaminated food or possibly, although rarely through direct inoculation following a blood transfusion. Y. enterocolitica exhibits a biphasic lifestyle which facilitates existence in terrestrial/aquatic and mammalian environments. Multiple Y. enterocolitica virulence factors have been identified including the expression of the structural and effector components of the type three secretion system, invasins (inv), adhesins and flagellar-mediated motility.
The expression of Y. enterocolitica virulence genes is tightly regulated by a range of environmental factors with temperature and population density playing a significant role.
Research areas:
The link between quorum sensing and swimming and swarming motility and the expression of the type three secretion system..
The genetic differences that define new- and old-world strains.
The role of adhesins in infection.
Y. enterocolitica is a mammalian enteropathogen which can present in humans as enteritis, enterocolitis, mesenteric lymphadenitis or terminal ileitis normally after the consumption of contaminated food or possibly, although rarely through direct inoculation following a blood transfusion. Y. enterocolitica exhibits a biphasic lifestyle which facilitates existence in terrestrial/aquatic and mammalian environments. Multiple Y. enterocolitica virulence factors have been identified including the expression of the structural and effector components of the type three secretion system, invasins (inv), adhesins and flagellar-mediated motility.
The expression of Y. enterocolitica virulence genes is tightly regulated by a range of environmental factors with temperature and population density playing a significant role.
Research areas:
The link between quorum sensing and swimming and swarming motility and the expression of the type three secretion system..
The genetic differences that define new- and old-world strains.
The role of adhesins in infection.